With Christian McCaffrey already on the injured reserve, Deebo Samuel has been ruled out due to injury for Week 3 in Los ...

The San Francisco 49ers will likely be without All-Pro tight end George Kittle for Sunday's game against the Los Angeles Rams ...

Kyle Shanahan didn't appear concerned about Jimmy Garoppolo's knowledge of the 49ers providing the Los Angeles Rams an ...

Fox Sports' Colin Cowherd voiced doubt about Brock Purdy's ability to succeed while a handful of 49ers stars are sidelined ...

In Week 3, wide receiver Jordan Whittington and the Los Angeles Rams' passing attack will take on the San Francisco 49ers and ...

George Kittle, Deebo Samuel, and Christian McCaffrey have all scored multiple touchdowns in the 49ers’ recent visits to SoFi ...

Hufanga didn’t participate in training camp, but got close enough to returning to come off the Physically Unable to Perform ...

The San Francisco 49ers (1-1) are visiting the Los Angeles Rams (0-2) on Sunday afternoon in a rivalry game between NFC West ...

Brock Purdy has faced the Vikings twice in his career. In both games, he turned the ball over twice, led the 49ers to just 17 ...

The 49ers are likely to be without George Kittle, Christian McCaffrey and Deebo Samuel for Sunday's game at the Rams.

Sean McVay shared injury updates ahead of Sunday’s game, already ruling out two players and listing three as questionable ...

San Francisco 49ers quarterback Brock Purdy will be tested in the coming weeks with the absence of key offensive weapons.