It's only Week 3, but both the 49ers and Rams are dealing with several key injuries entering Sunday's game. For San Francisco ...

Greg Scholz runs through the biggest fantasy football injury worries of Week 3, leading off with A.J. Brown's precarious ...

Samuel (calf) has been ruled out for Sunday's game against the Rams, Matt Barrows of The Athletic reports.

Brock Purdy plays much better with Deebo Samuel than without him. That's a fact. This Sunday, Purdy and the 49ers will have ...

Kyle Shanahan explained to NBC Sports Bay Area’s Greg Papa on “49ers Game Plan" why San Francisco's offense won’t change ...

The 49ers are likely to be without Christian McCaffrey, Deebo Samuel and now George Kittle against the Rams on Sunday ...

The 49ers revealed their status reports Friday for their injured players ahead of Sunday’s visit to the Los Angeles Rams.

The 49ers revealed their status reports Friday for their injured players ahead of Sunday’s visit to the Los Angeles Rams.

With Christian McCaffrey already on the injured reserve, Deebo Samuel has been ruled out due to injury for Week 3 in Los ...

Sunday’s NFC West showdown between the San Francisco 49ers and Los Angeles Rams could be an ugly affair, as both teams are ...

The San Francisco 49ers will likely be without All-Pro tight end George Kittle for Sunday's game against the Los Angeles Rams ...

Two of the best wide receivers in the NFL are expected to be on the field for their respective Week 3 games. Justin Jefferson ...